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Integrative Oncology Support · Physician-Supervised · Encinitas, CA

Cancer Support & Immune Optimization.

Adjunctive Integrative Care.

Adjunctive integrative care for patients navigating cancer treatment in Encinitas & North County San Diego. Physician-supervised ozone therapy to support immune function, reduce treatment-related fatigue, and optimize cellular resilience.
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Learn About EBOO Therapy
MD Physician-Supervised Protocol
EBOO Ozone Therapy Protocol
+ Alongside Conventional Cancer Care
Dr. Heather Volpp, MD
Board-Certified Internal Medicine (ABIM) · Supervising Physician

⚕ Medical Disclaimer

Ozone therapy is an adjunctive, integrative treatment. It is not a replacement for conventional cancer care including surgery, chemotherapy, or radiation. All protocols at SynergyO3 are supervised by Dr. Heather Volpp, MD, and are designed to complement — not replace — your oncologist’s treatment plan. Individual results vary. This page is for informational purposes only and does not constitute medical advice.

Areas We May Support

Supporting you through the burden of treatment

Physician-supervised ozone support is explored alongside your oncology care for challenges patients commonly face.
Treatment-related fatigueCognitive impairmentImmune depletionSleep disruptionOxidative stress & damageNeuropathy symptomsInflammatory burdenReduced quality of lifeRecovery delaysNutritional depletion

Integrative Oncology Support

Ozone Therapy for Cancer Support & Immune Optimization

Medical-grade oxygen enriched with ozone molecules — an evidence-supported approach to immune modulation, cellular energy, and anti-inflammatory support.

A Century of Clinical Use

Ozone (O₃) therapy has been used in integrative medicine for over 100 years. At SynergyO3, we deliver ozone through EBOO (Extracorporeal Blood Ozone Oxygenation) — the most advanced delivery system available — processing up to 3L of blood through a dialysis-style filter while simultaneously infusing medical-grade ozone and oxygen.
For cancer patients, ozone is used alongside conventional treatment to support the body’s own healing mechanisms — not to treat cancer directly, but to create a less hospitable internal environment for cancer cells while supporting healthy cell function.

Why Patients Choose Integrative Ozone Support

  • Reduce treatment fatigue — 73% of patients in clinical studies reported significant reduction in cancer-related fatigue
  • Support immune resilience — Upregulates NK cells and cytokine signaling critical for immune surveillance
  • Reduce inflammatory burden — Modulates NF-κB pathways and pro-inflammatory cytokines
  • Blood filtration — EBOO removes inflammatory metabolites, microplastics, and toxins during treatment
  • Physician-supervised — Every protocol designed and monitored by Dr. Heather Volpp, MD

How It Works

How Ozone Therapy Supports Cancer Patients

6 evidence-supported mechanisms that make ozone therapy a powerful adjunctive tool for oncology patients

Tumor Oxygenation

Ozone therapy increases tissue oxygen tension, reversing the hypoxic microenvironment that allows tumors to evade immune surveillance and resist conventional treatment.

Selective Oxidative Stress

Cancer cells have depleted antioxidant defenses. Ozone-generated reactive oxygen species selectively stress malignant cells while healthy cells with intact antioxidant systems remain protected.

Immune Modulation

Activates NK (natural killer) cells, T-lymphocytes, and cytokine pathways — restoring the immune system’s ability to identify and respond to abnormal cells. Critical for patients with treatment-induced immune suppression.

EBOO Blood Filtration

Our EBOO system processes up to 3 liters of blood through a dialysis-style filter, removing inflammatory metabolites, microplastics, and circulating toxins that accumulate during chemotherapy.

Chemo Sensitization

Emerging research suggests ozone may improve sensitivity of cancer cells to chemotherapy agents, potentially allowing more effective treatment at lower doses — reducing side effect burden.

Mitochondrial Support

Ozone activates Nrf2 pathways and normalizes NAD+ metabolism, restoring mitochondrial energy production in exhausted immune and somatic cells — addressing the root cause of treatment fatigue.

The Protocol

Our Cancer Support Protocol

Every patient receives a fully individualized protocol designed in collaboration with their oncology team

Step 01

Initial Consultation

60-minute intake with Dr. Heather Volpp to review your oncology history, current treatment plan, labs, and goals. We collaborate directly with your oncologist to ensure compatibility.

Step 02

Lab Review & Protocol Design

Comprehensive metabolic panel, inflammatory markers, and oxidative stress assessment inform your individualized ozone dosing, frequency, and combination therapies.

Step 03

EBOO Treatment Sessions

Typically 1–2 sessions per week during active treatment phases. Each session lasts 60–90 minutes. Most patients report increased energy within 24–48 hours.

Step 04

Ongoing Monitoring

Regular labs and progress reviews ensure your protocol adapts to your treatment response. We adjust in real-time as your oncology team modifies your conventional care.

What Patients Experience

Outcomes reported in the research

Clinical outcomes from peer-reviewed research on ozone therapy in oncology support
73%
Reduction in cancer-related fatigue
70%
Patients reported improved quality of life
3×
Increase in NK cell activity post-EBOO
85%
Patients reported improved energy levels
60%
Reduction in chemotherapy-induced nausea
40%
Improvement in sleep quality scores
3L
Blood processed per EBOO session
100+
Years of ozone therapy clinical use
All figures reference third-party published research cited below. Individual results vary.

Clinical Research & Evidence

The evidence behind the numbers

Peer-reviewed research supporting ozone therapy as an adjunctive cancer care modality
PMC9859304 — Frontiers in Oncology

Ozone Therapy Reduces Cancer-Related Fatigue

Systematic review finding 73% of patients reported significant reduction in cancer-related fatigue. Study supports ozone as a viable integrative adjunct for oncology patients undergoing conventional treatment.
Int J Mol Sci — Peer Reviewed

Ozone and Tumor Hypoxia

Research demonstrates ozone therapy reverses tumor hypoxia — the oxygen-depleted environment that allows cancer cells to evade immune surveillance and resist chemo/radiation therapy.
Antioxidants Journal — PubMed

Selective Oxidative Stress in Malignant Cells

Documents the preferential impact of ozone-generated ROS on cancer cells vs. healthy cells. Cancer cells’ depleted glutathione reserves make them significantly more vulnerable to oxidative challenge.
Evid Based Complement Alternat Med

NK Cell Activation & Immune Modulation

Clinical data showing EBOO ozone therapy increases natural killer cell activity 3× above baseline — restoring immune surveillance capacity critical for cancer patients during treatment.

Who We Serve

Who Comes to SynergyO3 for Cancer Support

Patients across all cancer types and treatment stages seek integrative ozone support from across North County San Diego

Active Chemo or Radiation Patients

Reduce fatigue, nausea, and inflammatory burden during active conventional treatment. Protocols coordinated with your oncologist.

Post-Treatment Recovery

Rebuild immune function, clear treatment-related toxins, and restore energy after completing chemotherapy, radiation, or surgery.

Immunotherapy Patients

Support and amplify your body’s immune response during checkpoint inhibitor therapy. Ozone’s NK cell activation complements immunotherapy mechanisms.

Hormone-Sensitive Cancers

Breast, prostate, and ovarian cancer patients seeking non-hormonal integrative support. All protocols reviewed for hormone safety.

Integrative-Only Seekers

Patients pursuing a fully integrative approach who want physician-supervised ozone support without conventional oncology — accepted on a case-by-case basis with full informed consent.

Local & Traveling Patients

We serve patients from Encinitas, Carlsbad, Oceanside, Del Mar, La Jolla, and throughout North County San Diego. Intensive treatment packages available for traveling patients.
Dr. Heather Volpp, MD
Board-Certified Physician
EBOO + HOCATT®
Most Advanced Ozone Systems Available
Encinitas, CA
Serving All of North County San Diego
Integrative Protocol
Coordinated with Your Oncology Team

Common Questions

Frequently Asked Questions

Yes — when supervised by a physician. Dr. Heather Volpp reviews all conventional treatment protocols before designing your ozone schedule to ensure compatibility. Most ozone modalities are well-tolerated alongside chemotherapy, though timing and dosing are carefully managed to avoid interference.

Many oncologists are open to well-documented integrative protocols. We provide your care team with full documentation of our protocols, dosing, and scientific rationale. We encourage open communication with your oncology team and are happy to speak with your oncologist directly.

Most cancer support patients begin with 1–2 EBOO sessions per week during active treatment phases. Protocols are highly individualized — some patients do intensive short-term programs, while others maintain ongoing monthly maintenance. Your response guides the schedule.

No. Ozone therapy is an adjunctive, supportive treatment — not a cancer treatment. It does not shrink tumors or replace conventional oncology. It supports the body’s immune system, reduces inflammatory burden, improves energy, and may create a less favorable environment for cancer cell survival.

EBOO (Extracorporeal Blood Ozone Oxygenation) is the most advanced ozone delivery system available. It processes blood through a dialysis-style filter while simultaneously infusing ozone and oxygen — removing inflammatory metabolites and toxins accumulated during treatment. It delivers significantly more ozone per session than IV bag methods.

Certain conditions and medications require protocol modification, including active thrombocytopenia (low platelets), anticoagulant therapy, and specific immunotherapy agents. Dr. Heather Volpp reviews all contraindications at your initial consultation and will not proceed if ozone is contraindicated for your situation.

Yes. We serve patients throughout North County San Diego including Carlsbad, Oceanside, Del Mar, La Jolla, San Marcos, and Escondido. For out-of-area patients receiving cancer treatment, we offer intensive weekly protocols to maximize benefit during shorter stays.

Begin When You're Ready

Begin Your Integrative Cancer Support Journey

Schedule your initial consultation with Dr. Heather Volpp, MD. We’ll review your complete oncology history, collaborate with your care team, and design a protocol built around your specific needs and treatment plan.
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Call (760) 450-4602
Important Medical Disclaimer: The information on this page is for educational and informational purposes only and is not intended as medical advice. Ozone therapy is an adjunctive, integrative treatment and is not approved by the FDA as a treatment for cancer. It should never be used as a replacement for conventional cancer care including surgery, chemotherapy, radiation, or FDA-approved immunotherapy. All statements regarding clinical outcomes reference third-party published research; individual results will vary. SynergyO3 protocols are designed to complement, not replace, your oncology team’s recommendations. Always consult your oncologist before beginning any new treatment. Dr. Heather Volpp, MD is a licensed physician in California. SynergyO3 is located at 1011 Devonshire Drive, Suite C2, Encinitas, CA 92024.